Liyuan Wang, PhD

Research Interests

• Epigenetic mechanisms employed by plant pathogens to evade host immunity and enhance virulence.
  • Histone modification, small RNA, mRNA NAD⁺ cap, DNA modification…
• Application of artificial intelligence in bioinformatics.

Education

• 2015.09 - 2021.06 – PhD, Plant Pathology, Nanjing Agricultural University, Nanjing, China
• 2019.01 - 2020.09 – Visiting student, Agriculture and Agri-Food Canada, London Research & Development Centre, London, Canada
• 2011.09 - 2015.06 – BSc, Plant Protection, Zhejiang Agriculture and Forestry University, Hangzhou, China
• 2014.05 - 2014.08 – Visiting student, China National Rice Research Institute, Hangzhou, China

Publications

1. Effector gene silencing coordinated by histone methylation and small RNAs enhances host adaptation in a plant pathogen. (Manuscript under submission; first author and co-corresponding author)
2. Wang, L., Xia, Y. and Hou, Y. (2024) Candy or poison: Plant metabolites as swing factors against microbes. Mol Plant, 17, 1341-1343.
3. Wang, L., Chen, H., Li, J., Shu, H., Zhang, X., Wang, Y., Tyler, B.M. and Dong, S. (2020) Effector gene silencing mediated by histone methylation underpins host adaptation in an oomycete plant pathogen. Nucleic Acids Res, 48, 1790-1799.
4. Wu, Y., Xu, P., Wang, L., Liu, S., Hou, Y., Lu, H., Hu, P., Li, X. and Yu, X. (2025) scGO: interpretable deep neural network for cell status annotation and disease diagnosis. Brief Bioinform, 26.
5. Wu, Y., Shao, W., Liu, S., Wang, L., Xu, P., Zhang, X., Song, H., Li, X., Wang, J. and Yu, X. (2025) Simultaneous profiling of ac4C and m5C modifications from nanopore direct RNA sequencing. Int. J. Biol. Macromol, 305.
6. Chen, H., Shu, H., Wang, L., Zhang, F., Li, X., Ochola, S.O., Mao, F., Ma, H., Ye, W., Gu, T. Jiang, L., Wu Y., Wang Y., Kamoun S. and Dong, S. (2018) Phytophthora methylomes are modulated by 6mA methyltransferases and associated with adaptive genome regions. Genome Biol, 19, 181.
7. Hou, Y., Wang, L., Wang, L., Liu, L., Li, L., Sun, L., Rao, Q., Zhang, J. and Huang, S. (2015) JMJ704 positively regulates rice defense response against Xanthomonas oryzae pv. oryzae infection via reducing H3K4me2/3 associated with negative disease resistance regulators. BMC Plant Biol, 15, 286.
8. Ochola, S., Huang, J., Ali, H., Shu, H., Shen, D., Qiu, M., Wang, L., Li, X., Chen, H., Kange, A. et al. (2019) Editing of an effector gene promoter sequence impacts plant - Phytophthora interaction. J Integr Plant Biol, 62, 378-392.

Grants / Funding

• National Natural Science Foundation of China (NSFC), Youth Project, Grant No. 32400164, 2025.01 – 2027.12
• China Postdoctoral Science Foundation, Grant No. 2022M712097, 2022.01 – 2023.08

Academic Service

• Youth Editorial Board Member, Genomics communications, 2024.11 – present

Honors / Awards

• 2022.12 | Jiangsu Province Outstanding Ph.D. Dissertation Award
• 2022.06 | Outstanding Dissertation Award, Nanjing Agricultural University
• 2022.05 | “Morning Star Postdoctoral Fellowship”, Shanghai Jiao Tong University
• 2021.06 | Outstanding Graduate, Nanjing Agricultural University
• 2020.12 | “Most Influential Graduate Student of the Year”, Nanjing Agricultural University (Top 10 Awardees)
• 2020.12 | First Prize, Graduate Academic Competition, Nanjing Agricultural University (Top 2 Awardees)
• 2020.06 | President's Scholarship, Nanjing Agricultural University (Top 8 Awardees)
• 2019.01 | Sinochem Agricultural MAP Scholarship (Top 8 Awardees)
• 2018.04 | Best Poster Award, 19th Oomycete Molecular Genetics Network Meeting